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Lrrk2 (leucine rich repeat kinase 2) is a protein coding gene Aberrant expression of this gene in adult tissues is associated with tumorigenesis. Diseases associated with lrrk2 include parkinson disease 8, autosomal dominant and parkinson's disease.
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Function, proteins, disorders, pathways, orthologs, and expression. This gene encodes a transcription factor containing a pou homeodomain that plays a key role in embryonic development and stem cell pluripotency The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis.
This receptor also functions as a receptor for the secondary bile acid, lithocholic acid.
Function, proteins, disorders, pathways, orthologs, and expression Complete information for alk gene (protein coding), alk receptor tyrosine kinase, including
Gene Hackman Gas Leak Most Recent Content Files #722
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